Nursing education and regulation: international profiles and perspectives

This review of nurse education and regulation in selected OECD countries forms part of ongoing work on contemporary nursing careers and working lives, based at the National Nursing Research Unit, King’s College London. The review was commissioned by the Department of Health to inform their work in considering the UK’s position in relation to the Bologna declaration and changes that may emanate from the implementation of Modernising Nursing Careers (DH 2006). While much of the information in the review was obtained from publications and websites, we also contacted key personnel in most of the countries included for an up-to-date review of developments in their country and would like to thank them all for providing this information

NCLB Reauthorization: Prospects and Opportunities for the Afterschool Field

Provides an introduction to No Child Left Behind legislation and the NCLB reauthorization debate. Highlights the links to afterschool policy and opportunities for advocacy

Theoretical development and social capital measurement

Chapter 4, by Sarah Hean and colleagues, highlights the importance of theory development in making the concept useful to the practice of public health. The authors present an innovative way of thinking about the different facets of social capital, describe the development of a survey instrument that attempts to make explicit the inputs and outputs of social capital and describe how these can be operationalised in a practice setting. The survey tool takes account of the dynamic nature of social capital and offers a useful way of evaluating community projects

Businessmen and benefactors: The Macclesfield silk manufacturers and their support for the town's charitable institutions, 1750-1900

This is the author's PDF version of an article published in Transactions of the Historic Society of Lancashire and Cheshire© 2008. Reproduced with permission of the Society of Lancashire and Cheshire.This article discusses how Macclesfield silk manufacturers contributed towards the development of voluntary organisations as part of their public role, using Sunderland Street Wesleyan chapel and the ragged and industrial school as examples. It explores the general reasons behind their charitable involvement and the extent to which their contribution was critical to the success of Sunderland Street Wesleyan chapel and the ragged and industrial school

The charitable work of the Macclesfield silk manufacturers, 1750-1900

The existing literature on philanthropic effort during the eighteenth and nineteenth centuries has taken a number of different approaches to the subject. These include general works charting the development of the charitable sector, the exploration of voluntary organisations as a subsidiary topic to broader themes and regional studies adopting a range of perspectives. Most research in this latter category has been conducted on large towns and cities that generally have copious amounts of source material. In contrast, lesser provincial towns have received relatively little scholarly attention, despite the more manageable nature of their documentation. The aim of this thesis is to explore the growth of charitable organisations within Macclesfield, an East Cheshire industrial town that was dominated by the silk industry. This study concentrates on the period from 1750 to 1900, when the silk industry was dominant within the town and philanthropic activity was at its height. The town’s silk manufacturers were renowned for their charitable work and thus this research focuses on the extent to which this occupational group was critical in the development of Macclesfield’s voluntary institutions, the motives that lay behind their contributions, and their achievements. In order to see whether their involvement was typical of other businessmen, comparisons are drawn throughout with the charitable activities of contemporary entrepreneurs in a variety of urban settings. This study investigates the silk manufacturers’ participation in Macclesfield’s voluntary institutions in the fields of religion, education, public services and public amenities, together with any additional charitable acts. The evidence from all these areas suggests that in most cases the silk manufacturers were heavily involved in funding and managing these institutions. Their obvious motives reflected altruistic, religious and educational beliefs, but there were also a variety of other concerns that could have been contributory in determining their support for particular institutions. The primary achievement of Macclesfield’s voluntary sector was to provide a network of services that, in conjunction with later state initiatives, improved living standards for inhabitants by the end of the nineteenth century. This thesis gives an insight into the development of charitable institutions in a medium sized industrial town and demonstrates how one group of businessmen were able to dominate this field. Many silk manufacturers were generous in their support of charitable causes in Macclesfield, but the scale of their support did not match that of some other notable philanthropic families, such as the Crossleys of Halifax. The charitable work of the silk manufacturers appeared to be broadly similar to that of entrepreneurs in other small and medium sized industrial towns where they could form a dominant occupational group in public life. In larger towns and cities, this strong manufacturer influence was less evident and a greater range of other people contributed significantly to philanthropic institutions. This type of approach supplements the existing material on philanthropic effort during the long nineteenth century and overlaps a number of related subject areas, such as urban élite activity and the growth of the welfare state

The M-C-M' cycle and social capital.

Social capital has become a popular term over the past two decades amongst researchers, policy makers and practitioners from varied disciplines. This popularity, however, has resulted in a great deal of confusion over the nature and application of social capital in different contexts. This confusion has made it difficult to identify and measure social capital within the evaluation of specific social and health programmes, one of the aims of which may be to stimulate social capital. This paper identifies a theoretical model that seeks to capture the dynamic nature of social capital to assist in the development of research methods that will facilitate its measurement and exploration within such programmes. The model reported in the paper identifies the key components of social capital and expresses the relationship between those components in a dynamic system based on Marx's description of the process of capital (economic) exchanges expressed in the M-C-M' cycle. The M-C-M' cycle is the transformation of money (M) into commodities (C), and the change of commodities back again into money (M') of altered value. The emphasis within the paper is on the capital element of the concept and its transactional nature with the aim of avoiding the pitfall of attributing social capital in relation to social behaviours in isolation of context and interaction. Importantly, the paper seeks to distinguish the central elements of social capital from some of the antecedent factors and outcomes often attributed to and confused with social capital adding to the problem of providing valid measurement. The model is presented as the basis for the measurement of social capital within a transactional process involving the investment of social resources in a cyclical process, which may result in net gains or losses. This process is described as the R-C-R' cycle following Marx's model of economic capital, with the focus being on the transfer of social resources (R) rather than money (M). R represents an internal resource held by individuals, C the external resource or commodity they obtain from the network and the R' the internal resource of altered value. The possibilities of the model in assisting in the measurement of social capital specifically in assessing formal networks are explored

Pharmacological Modulation of the Mitochondrial Electron Transport Chain in Paclitaxel-Induced Painful Peripheral Neuropathy

AbstractPaclitaxel is an effective first-line chemotherapeutic with the major dose-limiting side effect of painful neuropathy. Mitochondrial dysfunction and oxidative stress have been implicated in paclitaxel-induced painful neuropathy. Here we show the effects of pharmacological modulation of mitochondrial sites that produce reactive oxygen species using systemic rotenone (complex I inhibitor) or antimycin A (complex III inhibitor) on the maintenance and development of paclitaxel-induced mechanical hypersensitivity in adult male Sprague Dawley rats. The maximally tolerated dose (5 mg/kg) of rotenone inhibited established paclitaxel-induced mechanical hypersensitivity. However, some of these inhibitory effects coincided with decreased motor coordination; 3 mg/kg rotenone also significantly attenuated established paclitaxel-induced mechanical hypersensitivity without any motor impairment. The maximally tolerated dose (.6 mg/kg) of antimycin A reversed established paclitaxel-induced mechanical hypersensitivity without any motor impairment. Seven daily doses of systemic rotenone or antimycin A were given either after paclitaxel administration or before and during paclitaxel administration. Rotenone had no significant effect on the development of paclitaxel-induced mechanical hypersensitivity. However, antimycin A significantly inhibited the development of paclitaxel-induced mechanical hypersensitivity when given before and during paclitaxel administration but had no effect when given after paclitaxel administration. These studies provide further evidence of paclitaxel-evoked mitochondrial dysfunction in vivo, suggesting that complex III activity is instrumental in paclitaxel-induced pain.PerspectiveThis study provides further in vivo evidence that mitochondrial dysfunction is a key contributor to the development and maintenance of chemotherapy-induced painful neuropathy. This work also indicates that selective modulation of the electron transport chain can induce antinociceptive effects in a preclinical model of paclitaxel-induced pain